| Product name: |
Robo2 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
ROBO2; KIAA1568; Roundabout homolog 2 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human ROBO2. AA range:237-286 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
151kD |
| GeneID: |
6092 |
| Human Swiss-Prot No: |
Q9HCK4 |
| Cellular localization: |
Membrane ; Single-pass type I membrane protein . |
| Background: |
The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014], |
