| Product name: |
SAMHD1 (phospho-Thr592) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
SAM domain and HD domain-containing protein 1 (EC 3.1.4.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000 |
| Immunogen: |
Synthesized phosho peptide around human SAMHD1 (Thr592) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
72kD |
| GeneID: |
25939 |
| Human Swiss-Prot No: |
Q9Y3Z3 |
| Cellular localization: |
Nucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. . |
| Background: |
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1(SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010], |
