| Product name: |
SH3TC2 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
SH3TC2; KIAA1985; PP12494; SH3 domain and tetratricopeptide repeat-containing protein 2 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human SH3TC2. AA range:390-430 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
145kD |
| GeneID: |
79628 |
| Human Swiss-Prot No: |
Q8TF17 |
| Cellular localization: |
plasma membrane,cytoplasmic vesicle,recycling endosome, |
| Background: |
This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons. [provided by RefSeq, Jul 2008], |
