| Product name: |
Siah-2 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
SIAH2; E3 ubiquitin-protein ligase SIAH2; Seven in absentia homolog 2; Siah-2; hSiah2 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human SIAH2. AA range:241-290 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
38kD |
| GeneID: |
6478 |
| Human Swiss-Prot No: |
O43255 |
| Cellular localization: |
Cytoplasm . Nucleus . Predominantly cytoplasmic. Partially nuclear. . |
| Background: |
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008], |
