| Product name: |
SLC4A8/10 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
SLC4A8; KIAA0739; NBC; NBC3; NDCBE1; Electroneutral sodium bicarbonate exchanger 1; Electroneutral Na(+)-driven Cl-HCO3 exchanger; Solute carrier family 4 member 8; k-NBC3; SLC4A10; NCBE; Sodium-driven chloride bicarbonate exchanger; Solute |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human SLC4A8/10. AA range:411-460 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
140kD |
| GeneID: |
57282/9498 |
| Human Swiss-Prot No: |
Q2Y0W8/Q6U841 |
| Cellular localization: |
Membrane ; Multi-pass membrane protein . |
| Background: |
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4′-Di-isothiocyanatostilbene-2,2′-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012], |