Synthesized peptide derived from human SPP2A AA range: 66-116
Storage:
-20C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Molecular Weight:
57kD
GeneID:
84888
Human Swiss-Prot No:
Q8TCT8
Cellular localization:
Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein ; Lumenal side . Colocalizes with palmitoylated and myristoylated proteins at the plasma membrane.
Background:
This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012],