| Product name: |
Synphilin-1 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
SNCAIP; Synphilin-1; Sph1; Alpha-synuclein-interacting protein |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human Synphilin-1. AA range:797-846 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
100kD |
| GeneID: |
9627 |
| Human Swiss-Prot No: |
Q9Y6H5 |
| Cellular localization: |
Cytoplasm . Detected in cytoplasmic inclusion bodies, together with SNCA. |
| Background: |
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson’s disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015], |
