| Product name: |
TIG1 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Retinoic acid receptor responder protein 1 (RAR-responsive protein TIG1;Tazarotene-induced gene 1 protein) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human TIG1 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
51kD |
| GeneID: |
5918 |
| Human Swiss-Prot No: |
P49788 |
| Cellular localization: |
Membrane ; Single-pass type III membrane protein . |
| Background: |
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008], |
