TINAG rabbit pAb – TO12693
TO12693
Size:Price:
50 µL$148.00
100 µL$248.00

Overview

Product name: TINAG rabbit pAb
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human TINAG AA range: 80-130
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 52kD
GeneID: 27283
Human Swiss-Prot No: Q9UJW2
Cellular localization: Secreted, extracellular space, extracellular matrix, basement membrane .
Background: This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman’s capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis. [provided by RefSeq, Nov 2011],