| Product name: |
TNF α Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:50 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
17,25kDa |
| GeneID: |
7124 |
| Human Swiss-Prot No: |
P01375 |
| Cellular localization: |
Secreted,Cell membrane |
| Background: |
TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions.. |
