| Product name: |
TREM-1 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
TREM1; Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354 |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from TREM-1 . at AA range: 40-120 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
26kD |
| GeneID: |
54210 |
| Human Swiss-Prot No: |
Q9NP99 |
| Cellular localization: |
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Recruited to lipid rafts when activated. .; [Isoform 2]: Secreted . |
| Background: |
triggering receptor expressed on myeloid cells 1(TREM1) Homo sapiens This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011], |
