| Product name: |
TRPV4 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
TRPV4 VRL2 VROAC |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human TRPV4. AA range:461-510 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
100kD |
| GeneID: |
59341 |
| Human Swiss-Prot No: |
Q9HBA0 |
| Cellular localization: |
Cell membrane . Apical cell membrane ; Multi-pass membrane protein . Cell junction, adherens junction . Cell projection, cilium . Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum. .; [Isoform 1]: Cell membrane .; [Isoform 5]: Cell membrane .; [Isoform 2]: Endoplasmic reticulum .; [Isoform 4]: Endoplasmic reticulum .; [Isoform 6]: Endoplasmic reticulum . |
| Background: |
transient receptor potential cation channel subfamily V member 4(TRPV4) Homo sapiens This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010], |
