| Product name: |
VAMP-1/2/3 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP2; SYB2; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP3; SYB3; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptob |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human VAMP-1/2/3. AA range:21-70 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
13kD |
| GeneID: |
6843/6844/9341 |
| Human Swiss-Prot No: |
P23763/P63027/Q15836 |
| Cellular localization: |
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 2]: Cytoplasmic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein . |
| Background: |
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014], |
