| Product name: |
Vinculin Rabbit pAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
CMD1W antibody, CMH15 antibody, metavinculin antibody, MVCL antibody, VINC antibody |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoidrepeatedfreeze-thawcycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
130kDa |
| GeneID: |
7414 |
| Human Swiss-Prot No: |
P18206 |
| Cellular localization: |
Cytoplasm,Cytoskeleton,Cell junction, Adherens junction |
| Background: |
Vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. |